| Biological Information | |
|---|---|
| Background Information: | MATK (Megakaryocyte-associated tyrosine kinase) is a non-receptor protein tyrosine kinase that belongs to the Src family of kinases. It is predominantly expressed in hematopoietic cells, particularly in megakaryocytes, platelets, and B cells.
Research has suggested that MATK may be involved in the development and progression of several types of cancer, including breast cancer, leukemia, and lymphoma. In breast cancer, MATK has been shown to be upregulated in a subset of tumors, and may promote cancer cell growth and survival. In leukemia and lymphoma, MATK has been shown to be involved in the regulation of cell survival and proliferation, and may be a potential therapeutic target for the treatment of these diseases. |
| Target Class: | Kinase |
| Accession Number: | NM_139354.3 |
| Target Name: | MATK |
| Target Aliases: | Megakaryocyte-Associated Tyrosine Kinase, CTK, HYL, CHK, Hematopoietic Consensus Tyrosine-Lacking Kinase, Tyrosine-Protein Kinase CTK, Protein Kinase HYL |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
MATK, active
10 µg of active MATK. C-terminal 6His-tagged, recombinant, human MATK full length.
Datasheets
16-056x Datasheet
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