| Biological Information | |
|---|---|
| Background Information: | CaM Kinase 1b (Calcium/calmodulin-dependent protein kinase 1b) is a serine/threonine protein kinase that belongs to the CaM Kinase family of kinases. It is a key mediator of intracellular calcium signaling and is involved in the regulation of a wide range of cellular processes, including synaptic plasticity, learning and memory, and gene expression. In the brain, CaM Kinase 1b is particularly important in the regulation of synaptic plasticity and learning and memory. It has been shown to play a role in long-term potentiation (LTP), a process by which synaptic strength is enhanced in response to repeated stimulation, and is necessary for certain forms of learning and memory.
CaM Kinase 1b is also involved in the regulation of gene expression, and has been implicated in the development and progression of several diseases, including cancer, cardiovascular disease, and neurological disorders. |
| Target Class: | Kinase |
| Family: | CAMK1 family |
| Accession Number: | XM_011531113.1 |
| Target Name: | CaM |
| Target Aliases: | PNCK, CaM Kinase I Beta, Pregnancy Up-Regulated Nonubiquitous CaM Kinase, BSTK3 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
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CaM Kinase 1β, active
10 µg of active CaM Kinase 1b. N-terminal GST-tagged, recombinant, full length, human CaMK1ßs
Datasheets
15-001x Datasheet
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