Biological Information | |
---|---|
Background Information: | Anti-VISTA Antibody [730804] is a mouse monoclonal antibody that detects human VISTA/B7-H5/PD-1H. VISTA (V-domain Ig suppressor of T cell activation), also known as platelet receptor Gi24, is a member of the Ig superfamily and is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. Gi24 interacts with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state; and promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. Provided as 25 μg of antibody in 50μL buffer. |
Target Class: | Checkpoint Receptor |
Target Name: | VISTA |
Usage | |
Product Type: | Antibodies |
Application: | Drug Discovery & Development |
Storage Conditions: | Store at -20°C. Please avoid multiple freeze/thaw cycles. |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Additional Information | |
Brand: | DiscoverX |
Anti-VISTA Antibody [730804]
Anti-VISTA Antibody [730804] is an antibody acting as an agonist for VISTA dimerization. This product is provided as 25 μg of antibody in 50μL buffer.
Datasheets
92-1311 Datasheet
View Document