Biological Information
Background Information:
Geldanamycin is an antibiotic and a potent inhibitor of the heat shock protein 90 (Hsp90) protein (KD=1.2uM), binding its ATP site and inhibiting its chaperone activity. Induces selective degradation of mutated versions of v-Src, Bcr-Abl, Raf, p53, and steroid receptors in tumor cells via Hsp90 inhibition. Affects multiple cellular processes, including gene expression, cell proliferation, apoptosis, and angiogenesis. Provided as 1 mg of dry powder.
Usage
Product Type:
Control Ligands & Inhibitors
Application:
Drug Discovery & Development
Storage Conditions:
Store at -20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®