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Screening & Profiling Services

- Information that drives decision making

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Profiling Services

DiscoveRx offers services for every step of the drug discovery process. Following the initial HTS campaign in your own facilities or through our Screening Services,
we are the perfect solution for hit-to-lead and lead optimization activities such as compound selectivity and rank order profiling.

We offer a flexible approach to screening:

Based on your needs, we can perform compound profiling against any panel of your choice at a single concentration or provide EC50/IC50 dose-response determinations. We also offer the flexibility of processing your compounds in agonist, antagonist, inverse agonist, or allosteric modes.

Our Service Include

High quality data
Competitive pricing
Complete confidentiality
Open business model - No minimum commitment
Multiple pharmacology measurement
20 day turnaround time

Request Additional Information

Take advantage of our capacity to rapidly generate screening data and move your projects ahead.

To learn more about our service, screening options and pricing, email us at: profiling@discoverx.com

Built-in Quality

A stringent validation process ensures the highest quality data possible. Each data point is performed in duplicate. Strict quality control protocols ensure that any assay results not meeting set specifications will be automatically repeated.

All of the DiscoveRx cell lines used in the Profiling Service provide superior response profiles as a result of optimization of assay conditions and selection of high-responding cell populations. We ensure the consistency, reliability, and performance of each cell line. In fact, the same cell lines that we use in our service can be purchased by our clients to perform internal follow-up experiments.

Profiling Panels

DiscoveRx provides broad panels of targets which can be utilized for selectivity screening of lead compounds. Based on your needs, we can also perform compound profiling against any custom panel.

Click on figure to enlarge

Figure 1. Profiling agonist panels of receptors in the same family can provide compound selectivity information.

Ordering Information

To learn more about our services, screening options, and pricing, please email us at profiling@discoverx.com or send in a Quote Request Form so we may send you a no obligation price quote

Available Literature

Click here to view what we have available!

Available Assays and Technologies

We have cell-based assays to address all major drug target classes.

For a complete list of available targets for screening and profiling services, please click on the appropriate links below.

Assay format

GPCRs

NHRs

Kinases

Pathway Assays

Biochemical Assays

Kinase Binding Assays

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Cell-Based Assays

β-Arrestin

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cAMP

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Calcium Flux

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Internalization

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Nuclear Translocation

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Protein Interaction

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Cell-Based Kinase Assays

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Pathway Assays

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