Bibliography

Posters

Target Title Assays Download
Kinases • ADP Hunter™ Plus: Extended Application for Detection of GDP and UDP Production ADP Hunter™ Plus
Pathway Analysis Utilization of PathHunter™ Arrestin Cell Lines for Detection of Arrestin Biased Ligands and Compound Pharmacology Distinct from Second Messengers PathHunter™ ß-Arrestin
GPCR Development of a Panel of cAMP Hunter™ Cell Lines for Analysis of Naturally Coupled GPCRs Using the DiscoveRx HitHunter™ cAMP Detection Kits HitHunter™ cAMP Detection Kits
GPCR HitHunter™ CAMP Assays: Versatile Assays Validated for Multiple Applications HitHunter™ cAMP Assays
GPCR Miniaturization of the HitHunter™ cAMP XS+ Assay for Gs/Gi Screening in 1536 Well Plate Format HitHunter™ cAMP XS+ Assay
GPCR Dual Purpose Cell Lines for Analysis of GPCR/Arrestin Interaction Using PathHunter™ and Natural Gq-Coupling Using the Improved Calcium No-Wash Plus (CaNW Plus) Kit. Calcium No Wash Plus (CaNW Plus)
Pathway Analysis Profiling for GPCR activation using DiscoveRx PathHunter™ B-Arrestin technology PathHunter™ B-Arrestin Assay
Kinases Optimized ADP Accumulation Assays for PI-3 Kinase for Primary Screening, Kinase and Kinase Inhibitor Characterization ADP PI-3K
Nuclear Hormone Receptors PathHunter™ NHR Protein Interaction Cell Lines: Study Nuclear Hormone Receptors without Using Reporter Gene Assays PathHunter NHR
Kinases ADP Hunter™ Plus: A Rapid Quantitative HTS Assay for GDP and UDP ADP Hunter™ Plus
Pathway Analysis Profiling for GPCR activation using DiscoveRx PathHunter B-Arrestin Technology Arrestin, Profiling
Pathway Analysis PathHunter B-Arrestin Assay for monitoring GPCR activation in the neuronal cell line SY5Y Arrestin
Pathway Analysis Identifying and Characterizing Cannabinoid CB2 Receptor Ligands using DiscoveRx PathHunter™ ß-Arrestin Assay PathHunter, B-arrestin
Kinases ADP Kinases assays from Discoverx, SBS07 tutorial ADP Hunter Plus, ADP Quest, ADP Quest HS, ADP Hunter HS
Pathway Analysis A Rapid Non-Imaging, Non-Reporter Gene Screening Assay Format for Analysis of Nuclear Receptor Function in Whole Cells. PathHunter™ NHR
Pathway Analysis Applications of EFC-based Protein-Protein Interaction Assays for Gi, Gs, and Gq-coupled GPCR Screening PathHunter™ ß-arrestin
Kinases ADP Hunter™ HS and Quest™ HS: Improved ADP accumulation assays for kinase primary screening and inhibitor characterization/lead optimization. ADP Hunter™ HS and Quest™ HS
GPCR Ultra High Throughput screening for antagonists of a Gi-coupled receptor in a 2.2 ul 3456-well plate format cAMP assay cAMP
Pathway Analysis Insulin-Stimulated GLUT4 Translocation Quantified by EFC PathHunter GLUT4 Translocation
GPCR Development of a Non-Imaging, Homogeneous Assay Format for Analysis of Arrestin Recuitment as a Detection Method for Generic GPCR Screening PathHunter™ ß-arrestin
Kinases ADP Hunter™ Plus: An Optimized Assay Format with Minimized Compound Interference for Kinase Primary Screening Using ADP Accumulation ADP Hunter™ Plus
Pathway Analysis Utilization of a Mitotic Index Biosensor in a Homogeneous Assay Format for Identification of siRNAs that Inhibit Mitosis PathHunter™ Mitotic Index
Pathway Analysis Application of a Homogeneous, Non-Imaging Cell-Based Assay for Rapid and Direct Detection of NHR Translocation PathHunter™ NHR Translocation
Kinases A Technique Using ß-Galactosidase (ß-Gal) Enzyme Fragment Complementation (EFC) to Directly Characterize Inhibitor Binding to Active and Unactive Kinases HitHunter™ Kinase Binding Assay
Proteases Novel Method to Detect Proteases using EFC Technology caspase 3, protease
GPCR Ca NW Poster - Boehringer Ingelheim Calcium Assays
GPCR A Novel Calcium No Wash Assay for Analysis of GPCR Signaling Calcium No Wash
Pathway Analysis A Homogeneous Assay to Monitor Cellular Mitosis using EFC (HCA 2006) PathHunter, Mitotic Index
Pathway Analysis Monitoring Translocation Activity of Transcription Factors and Nuclear Hormone Receptors Using EFC PathHunter CHO-K1 GR Assay, SBS 2005 @ Geneva
Pathway Analysis A Homogeneous Assay to Monitor Nuclear Hormone Receptor Degradation using Beta-Galactosidase Complementation PathHunter AR Degradation Assay, SBS 2005 @ Geneva
Kinases A Novel Kinase Assay Technology Applicable to Target Validation, Assay Development and Primary and Secondary Screening ADP Quest, ADP Hunter, TK Substrate Hunter - SBS 2005 @ Geneva
Kinases ADP HunterTM: a generic homogeneous assay for high throughput kinase inhibitor screening ADP Hunter @ SBS 2005 in Geneva
GPCR cAMP Detection Using Enzyme Fragment Complementation (EFC) Miniaturization and Automation for Production uHTS HitHunter cAMP I, HitHunter cAMP II
GPCR DiscoveRx HitHunter Enzyme Fragment Complementation Chemiluminescence Assay for the Detection of cAMP Production from Membranes and Whole Cells for GPCRs HitHunter cAMP - Generation I
Protein Expression A Novel Technology to Quantitatively Measure Protein Expression in Crude Cell Lysates ProLabel Solutions
Kinases A New High-Throughput Screening Platform for p38-MAP Inhibitors in a Kinase Binding Mode HitHunter p38 MAPK Binding Assay
Nuclear Hormone Receptors Homogenous Assays for Nuclear Hormone Recptors Using Enzyme Fragment Complementation HitHunter Estrogen Assay, HitHunter Progesterone Receptor Assay
Kinases ADP Quest, A Novel, Homogeneous, Generic Kinase Activity Assay ADP Quest
Proteases Novel Cortisol Detection Assay HitHunter Cortisol
Proteases A Novel Method to Detect Proetases Utilizing Complementation of Enzyme Fragments as a Signal Generation System HitHunter Caspase 3
GPCR An Improved Enzyme Fragment Complementation (EFC) Technology for Detection of cAMP in Miniaturised and Automated uHTS HitHunter cAMP II
GPCR A 1536-well cAMP Assay for Gs- and Gi-coupled Receptors HitHunter cAMP XS
Kinases ADP Quest - A novel, homogeneous, generic kinase activity assay ADP Quest
GPCR Novel Assay Platforms for Orphan GPCR High Throughput Screening HitHunter cAMP, HitHunter IP3
Kinases A Kinase Profiling and Screening System Using Fluorescent Polarization and Enzyme Fragment Complementation Assays HitHunter EFC Kinase, HitHunter FP Kinase
Kinases HitHunter Kinase assays: a comprehensive and homogeneous screening platform Kinome Hunter, Susbstrate Hunter, HItHunter Kinase FP Assay, HitHunter Kinase EFC Assay, HitHunter K

Published Papers

Target Title Assays Download
GPCR A 1,536-Well cAMP Assay for Gs- and Gi-Coupled Receptors Using Enzyme Fragment Complementation HitHunter cAMP I
Kinases A High-Throughput, Nonisotropic, Competitive Binding Assay for Kinases Using Nonselective Inhibitor Probes (ED-NSIPTM) HitHunter NSIP staurosporine
Kinases Enzyme Fragment Complementation: A Flexible High Throughput Screening Assay Technology All
GPCR A Homogeneous Enzyme FragmentComplementation Cyclic AMP Screen for GPCR Agonists HitHunter cAMP I

Published Reviews

Target Title Assays Download
Proteases ß-Galactosidase Enzyme Fragment Complementation as a High-Throughput Screening Protease Technology HitHunter Caspase Assay, HitHunter â-Secretase Assay
GPCR cAMP Detection Methods in HTS: Selecting the Best From the Rest HitHunter cAMP
GPCR A Homogeneous Enzyme Fragment Complementation Cyclic AMP Screen for GPCR Agonists HitHunter cAMP I

Flyers

Target Title Assays Download
Kinases • ADP Quest™ and ADP Quest™ HS ADP Accumulation Assay for Kinases and ATPases ADP Quest™ and ADP Quest™ HS
GPCR GPCR Profiling & Screening Services GPCR Profiling & Screening Services
Pathway Analysis PathHunter™ ß-Arrestin Assays PathHunter™ ß-Arrestin Assays
GPCR cAMP Hunter™ GPCR Cell Lines cAMP Hunter™
GPCR Coelenterazine h Coelenterazine h
EFC Enzyme Fragment Complementation Assay Technology EFC Technology
GPCR Revolutionize GPCR Drug Discovery GPCR Overview
Pathway Analysis PathHunter GPCR Profiling Services Flyer PathHunter
Kinases Universal ADP Detection for Change? ADP Hunter™ Plus & HS, ADP Quest™ & HS
Kinases PhosphoQuest™ ELISA Kits - Cell-Based Kinase Assays PhosphoQuest™ ELISA
Pathway Analysis PathHunter™ Flash Detection Kit PathHunter™ Flash Detection
Pathway Analysis PathHunter™ EAstern Blot Assay Kit PathHunter™ EAstern Blot Assay
Nuclear Hormone Receptors PathHunter™ Nuclear Translocation Assays PathHunter™ NHR
Pathway Analysis PathHunter™ ß-arrestin Assays - Over 101 GPCR Targets Qualified! PathHunter™ ß-arrestin Pools
Kinases ADP Hunter™ and ADP Quest™ Assays for Kinases and ATPases ADP Hunter™ and ADP Quest™
Nuclear Hormone Receptors PathHunter Nuclear Translocation Assays PathHunter Nuclear Translocation Assays
Pathway Analysis VectorsPools10_06 PathHunter
Pathway Analysis ProLabel Expression Vectors 9_23 PathHunter
Pathway Analysis ProLabel Expression Vectors PathHunter
GPCR HitHunter™ cAMP Assays - For all your cAMP needs HitHunter™ cAMP Assays
Kinases Finally, Include Unactive Kinases in Your Next Screening Campaign - HitHunter™ Kinase Binding Assays HitHunter™ Kinase Binding Assays
Pathway Analysis PathHunter™ ß-arrestin Assays ß-arrestin Assays
Pathway Analysis PathHunter™ Homogeneous Mitotic Index Assays Mitotic Index
Kinases ADP Hunter Plus and ADP Quest (flyer) ADP Hunter Plus, ADP Quest
GPCR DiscoveRx Calcium No Wash (CaNW) Plus Assay Kit Calcium No Wash (CaNW) Plus
Pathway Analysis PathHunter™ High Throughput Assays for Cellular Protein Trafficking PathHunter
Kinases Kinase Binding Assay Flyer Kinase Binding Assay
Kinases ADP Hunter Data Sheet ADP Hunter
GPCR GPCR cAMP Brochure HitHunter cAMP, HitHunter cAMP XP,
GPCR HitHunter cAMP II - 384-well HitHunter cAMP II
Other Oxygen Sensor Probe for cell viability Oxygen Sensor Probe
Other Ion Channel Cell Line - hERG data sheet Ion Channel Cell Line - hERG
Kinases ADP Quest - Product Flyer ADP Quest

Application Notes

Target Title Assays Download
GPCR 1536 Application for HitHunter™ cAMP XS+ using Deerac Equator™ HTS HitHunter™ cAMP XS+
Nuclear Hormone Receptors *** NEW *** PathHunter™ NHR Assays *** NEW *** PathHunter™ NHR Assays
Nuclear Hormone Receptors PathHunter NHR Cell-based Assays for Screening & Profiling PathHunter NHR PRO Assay
Pathway Analysis A Novel ß-arrestin Assay for Monitoring GPCR Activation PathHunter™ ß-arrestin Assays
Kinases 96-Well PhosphoQuest™ Sample Preparation for Suspension Cells PhosphoQuest™ Suspension Cells Application Notes
Kinases 96-Well PhosphoQuest™ Sample Preparation for Adherent Cells PhosphoQuest™ Adherent Cells Application Notes
Pathway Analysis PathHunter Webinar 5.18.07 PathHunter
Kinases Organon Presentation 2006:Binding Assays for Inactive Kinases Kinase Binding
GPCR Evaluation of a new intracellular calcium fluorescent reagent using the FDSS6000 CaNW
Kinases Evaluation of a homogeneous approach for identifying kinase inhibitors using HitHunter Kinase Binding Assays Kinase Binding Assay
GPCR New HitHunter cAMP XS+ Assay for GPCR Screening Using the PHERAstar cAMP XS+
GPCR Measurement of Phosphodiesterase Activity using HitHunter cAMP II HitHunter cAMP

 

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