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Kinase Screening & Profiling Services-DiscoveRx

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Kinases

– Screening & Profiling Services: Information that drives decision making

Kinase Screening & Profiling Services

Screen and Profile your compounds against 451 Kinases

PathHunter® Cell-Based Kinase Assays

Utilizing PathHunter® technology, DiscoveRx has found a new approach to studying receptor tyrosine kinases in a cellular context. Unlike biochemical assays that commonly use a truncated version of the receptor, PathHunter® Cell-Based Kinase assays utilize wild type, full length proteins which allow all steps in receptor activation be monitored. This whole cell assay platform is ideal for identifying novel receptor tyrosine kinase inhibitors, allosteric modulators or antibody therapeutics.

Receptor Tyrosine Kinase Panel

We currently have 20 cell-based kinase targets available for profiling, screening, and selectivity studies. We are continuing to develop additional targets in order to provide the most comprehensive panel.

Receptor Tyrosine Kinase Assays

Target
Product Name
Partner Protein
Details
Price
c-MET*
PathHunter® c-MET Functional Assay
GrB2
DDR2
PathHunter® DDR2 Functional Assay
PLCG1
EphB4*
PathHunter® ephB4 Functional Assay
SHC1

Cytosolic Tyrosine Kinase Assays

Target
Product Name
Partner Protein
Details
Price
CSF3R-JAK1
PathHunter® PRLR-JAK1 Functional Assay
SHC1
GHR-JAK1
PathHunter® PRLR-JAK2 Functional Assay
PLCG2
PRLR-JAK1*
PathHunter® PRLR-JAK1 Functional Assay
PLCG2
PRLR-JAK2*
PathHunter® PRLR-JAK2 Functional Assay
PLCG2

*Also available in a scheduled panel

 

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