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Kinases

– Universal Assays for Kinase Screening

HitHunter® Kinase Binding Assay Literature

Flyers/Brochures

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Title
Technology
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The Broadest Panel of Kinase Solutions for Characterization, Profiling & Screening
PathHunter® Kinase Overview
HitHunter® Kinase Binding Assays
Novel Antibody-Free Ligand Screening Assays for Active and Unactive Kianses, 2008
Finally, Include Unactive Kinases in Your Next Screening Campaign - HitHunter® Kinase Binding Assays
HitHunter® p38-MAP Kinase binding Assay, SBS 2006

Posters

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Technology
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A Technique Using β-galactosidase Enzyme Fragment Complementation to Directly Characterize Inhibitor Binding to Active and Unactive Kinases
HitHunter® p38-MAP Kinase binding Assays, SBS 2006
A New High-Throughput Screening Platform for p38-MAP Kinase Inhibitors in a Kinase Binding Mode
HitHunter® p38-MAP Kinase Binding Assays, SBS 2004

Presentations

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Title
Technology
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Evaluation of a homogeneous approach for the identification of kinase inhibitors, using β-galactosidase (β-gal) enzyme fragment complementation (EFC) assays - Astera Zeneca Presentation
Kinase Binding Assays, Screening Europe 2007
Kinase Compound Profiling at Organon - Organon presentation
Kinase Binding Assays, CHI Protein Kinase, 2006

Bibliography

Title
1. Vainshtein I., Silveria S., Kaul P., Rouhani R., Eglen R and Wang (2002) A High-Throughput, Nonisotopic,
    Competitive Binding Assay for Kinases Using Nonselective Inhibitor Probes (ED-NSIPTM) J. Journal of
    Biomolecular Screening,, 7(6): 507-514
2. Guido J.R. Zaman, Miranda M.C. van der Lee, Jacobus J. Kok, Rob L.H. Nelissen, Elma E.M.G. Loomans
    (2006) Enzyme Fragment Complementation Binding Assay for p38a Mitogen-Activated Protein Kinase to     Study the Binding Kinetics of Enzyme Inhibitors ASSAY and Drug Development Technologies. Aug 2006,
    Vol. 4, No. 4: 411-420
3. Wesche H., Xiao S-H, and Young S.W. (2005) High Throughput Screening for Protein Kinase Inhibitors.
    Combinational chemistry & High Throughput Screening 8:181-195
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