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-  Assays with the Broadest Kinome Coverage for Kinase Screening
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Assays with the Broadest Kinome Coverage for Kinase Screening

 

Overview & Description
Kinases are a large and complex class of highly druggable target proteins. DiscoveRx provides a wide variety of radioisotope-free assays with broad applicability in kinase drug discovery research and screening. These generic, no-wash assays include traditional antibody-based assays, as well as those that are require neither antibody or specialized substrate. Whether your screening is against active or unactive kinses, we have a solution that is right for you.

 

Key Features
• Novel screening assays for both unactive and active kinases
• Universal ADP detection and screening assays for all your kinases and ATPases
• Traditional assays using antibody-substrate pairs detected by EFC or FP with broad kinome coverage


Kinase Assay Selection Guide

 

ADP Hunter™ Plus and ADP Hunter™ HS Assays - Universal ADP detection assay for HTS

FL

X

X

X

 

X

 

X

 

 

 

X

 

ADP Quest™ and ADP Quest™ HS Assays - Universal ADP detection assay for kinetic characterization

FL

X

 

X

X

X

 

X

 

 

 

X

 

 

HitHunter™ Kinase Binding Assays - Competitive binding for unactive, low-activity, and active kinases

CL

 

X

X

 

 

X

 

 

X

 

 

 

HitHunter™ EFC Kinase Assays - Screening assays for kinases with known antibodies and substrates

CL

 

X

 

 

X

 

 

 

 

 

 

 

HitHunter™ FP Kinase Assays - Screening assays with known antibodies and substrates

FP

 

X

 

 

X

 

 

 

 

 

 

 

TK Substrate Quest™ Assays - Identification of substrates for tyrosine kinases

FL

 

 

 

 

X

 

 

 

 

X

 

 

Phospho Quest™ Assays - ELISA assays for detecting phosphorylated proteins

CO

 

 

 

 

X

 

X

X

 

 

 

 

READ OUT KEY

 

CL Chemiluminescent
FL Fluorescent
FP Fluorescence polarization
CO Colorometric


Don't See What You Need?
Please vist our Custom Services or contact us for your custom assay development.