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GPCR Screening & Profiling Services
DiscoveRx offers the largest collection of validated GPCR functional assays for screening and profiling. Our PathHunter® β-Arrestin technology is a direct, universal platform for measuring compound action independent of G-protein signaling through β-Arrestin recruitment to the GPCR. We also offer second messenger detection of cAMP and calcium mobilization in naturally coupled systems. Utilizing multiple approaches can provide valuable information in a high biological context and lead to novel drug discovery.
PathHunter® β-Arrestin Assays, cAMP Hunter™ Assays, Calcium No WashPLUS Assay
G Protein-Coupled Receptor Panel
We have 300 GPCR functional cell-based assays for compound library screening, profiling, selectivity studies or full panel screens. For our list of available orphan receptor targets, please click here.
Available Collaterals
click here to view what we have available!
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