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DiscoveRx: GPCR - Assay-Ready: EasyScreen™ β-Arrestin GPCR Kits

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GPCR

- Assay-Ready: EasyScreen ß-Arrestin GPCR Kits

EasyScreen™ β-Arrestin GPCR Kits


Fast and Simple Confirmation Screens without the Cell Culture

EasyScreen™ provides you with a fast and simple tool to perform small screens on a variety of lead compounds, peptides or natural ligands without the lengthy and time consuming cell culture or assay development. Using this fast and simple β-Arrestin-based screening assay, you can rule out false positive hits from a Calcium or cAMP primary screen or validate your second messenger hits using an alternative, non-G-protein mediated signaling pathway (Figure 1).

For instrument compatibility, please click here.

HTS-Friendly Screening Tool

Each EasyScreen kit includes everything needed for monitoring GPCR activation in live cells. Assay-ready frozen cells are provided in single use vials; simply thaw and plate the cells, and run the screen 24 hours later. Kits also include chemiluminescent detection reagents, assay buffer and an optimized protocol developed for 384-well plate analysis.

Available Collaterals

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Targets
Catalog #
Cell Line
Datasheet
Price
ADCYAP1R1
93-0249E2C1L
CHO
ADORA1
93-0185E2C1L
CHO
ADORA3
93-0586E2C2L
CHO

 

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