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Second Messenger Cell Lines, GPCRS Screening

PRODUCTS & SERVICES

GPCR

- Leading Portfolio of Non-force Coupled Cell Lines for Functional GPCR Screening

Second Messenger Cell Lines

Expedite your screening with native, non-force coupled, stable clonal cell lines expressing Gs, Gi, or Gq coupled GPCR. A wide menu of fully optimized, target-validated GPCR cell offers you convenience, relevant hits and guaranteed performance.

Product Features

 GPCR cell lines with no force-coupling
 Fully characterized for pharmacology, specificity & passage stability
 Optimized protocol available with all cell lines reducing assay development time

Applications

 Obtain smarter hits, quicker lead compounds with high performing cell lines
 Ideal for functional second messenger screening campaigns
 Well-suited for ligand profiling, antibody therapeutics, membrane preparations

Available Literature

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Validated cAMP Hunter™ Gs/Gi Cell Lines ( > 107 )

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Targets
Catalog #
Available Profiling
Datasheet
Price
ADCYAP1R1 (PAC1)
95-0064C2
Yes
ADORA1
95-0061C2
Yes
ADORA2B
95-0041C2
Yes

Validated Calcium Gq Cell Lines

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Targets
Catalog #
Available Profiling
Datasheet
Price
ADORA2A
95-1008C11
Yes
BDKRB1
95-1011C2
Yes
BRS3
95-1001C2
Yes
CYSLTR2
95-1013C2
Yes
EDG3
95-1007C2
Yes
EDG4
95-1012C2
Yes
F2RL1
95-1006C2
Yes
FFAR1 (GPR40)
95-1005C2
Yes
FFAR2 (GPR43)
95-1002C2
Yes
GALR2
95-1010C2
Yes
GNRHR
95-1004C2
Yes
GPR39
95-1015C3
No
OXGR1
95-1017C3
No
P2RY1
95-1018C6
No
PTGER1
95-1003C2
Yes
PTGFR
95-1009C2
Yes

New! Custom bulk cell options are available with the purchase of any
(cAMP Hunter™) clone. Package sizes range from 100 million to 2 billion cells.

Don't see your target?

Click here to explore our Custom Assay Development possibilities.

 

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