PathHunter™ β-Arrestin Ortholog GPCR Assays

 

PathHunter™ β-Arrestin ortholog GPCR assays are offered by DiscoveRx to facilitate counterscreening and SAR evaluation of compounds identified in primary screening of human GPCR targets. Gain greater understanding of your putative leads, determine mechanism of action, or delineate differential ligand-activated responses of lead compounds prior to testing in expensive animal models.

Product Features

•Over 80 Mouse and Rat β-Arrestin Ortholog GPCR Assays available
•Fully validated, functional clonal cell lines expressing ortholog GPCRs
•Optimized to detect a full range of compound pharmacologies
•Detect species selective agonists, superagonists, or do selectivity compound
profiling on a panel of lead compounds

For instrument compatibility, please click here.

Identify Species Selectivity of Your Compound

(click on figures to enlarge)

Don't see your target?

Click here to explore our Custom Assay Development possibilities.

Don't want to do cell culture?

New! Custom bulk cell options are available with the purchase of any PathHunter clone. Package sizes range from 100 million to 2 billion cells. Frozen, assay-ready bulk cells will expedite your screening campaigns and ensure reproducible results. Bulk cells are functionally tested for optimal assay performance and are confirmed to be Mycoplasma-free. Click here for a quote.

 

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