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PathHunter® β-Arrestin Ortholog GPCR Assays
PathHunter® β-Arrestin ortholog GPCR assays are offered by DiscoveRx to facilitate counterscreening and SAR evaluation of compounds identified in primary screening of human GPCR targets. Gain greater understanding of your putative leads, determine mechanism of action, or delineate differential ligand-activated responses of lead compounds prior to testing in expensive animal models.
Product Features
Over 80 Mouse and Rat β-Arrestin Ortholog GPCR Assays available
Fully validated, functional clonal cell lines expressing ortholog GPCRs
Optimized to detect a full range of compound pharmacologies
Detect species selective agonists, superagonists, or do selectivity
compound profiling on a panel of lead compounds
For instrument compatibility, please click here.
Identify Species Selectivity of Your Compound
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Download the user manual 
Don't see your target?
Click here to explore our Custom Assay Development possibilities.
New! PathHunter® Certified Cell Plating Reagents & Control Ligands
All PathHunter® Certified reagents have been designed, validated and optimized for use with each PathHunter® cell-based assay. Each PathHunter® cell-based assay combines pre-validated cell lines and reagents, providing you a convenient solution to minimize assay development and ensure optimal and reproducible results every time. Learn More»
Don't want to do cell culture?
New! Custom bulk cell options are available with the purchase of any PathHunter® clone. Package sizes range from 100 million to 2 billion cells. Frozen, assay-ready bulk cells will expedite your screening campaigns and ensure reproducible results. Bulk cells are functionally tested for optimal assay performance and are confirmed to be Mycoplasma-free. Click here for a quote.
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