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Janus kinase 2 (JAK2(JH1domain-catalytic))

Target Class
Kinase
Family
TK
Official Symbol
JAK2
Entrez Gene ID
3717
Species
Human
Accession Number
NP_004963.1
Alias Names
JAK-2; JTK10; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); THCYT3; tyrosine-protein kinase JAK2
Background
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Group Members: TK
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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