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mitogen-activated protein kinase 3 (ERK1(Q122L))

Target Class
Kinase
Family
CMGC
Official Symbol
MAPK3
Entrez Gene ID
5595
Species
Human
Accession Number
NP_002737.2
Alias Names
ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAPK 1; P44ERK1; P44MAPK; PRKM3; extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; insulin-stimulated MAP2 kinase; microtubule-associated protein 2 kinase; mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; p44-ERK1; p44-MAPK
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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