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UNC 0638

UNC 0638 is a cell permeable synthetic small molecule inhibitor of the G9a and GLP histone lysine methyltransferase enzymes (IC50 of <15nM and 19nM, respectively), which contribute to early embryogenesis, genomic imprinting, and lymphocyte development. >1000-fold selective vs other HMTases.

Catalog No. Size Price Quantity
92-1150 10 mg $409.00
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Description
UNC 0638
Compound Type
Antagonist
Storage
2-8◦C
Source
Synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control compound, using the assay conditions described below. Following treatment, signal was detected using the InCELL Hunter Detection Kit according to the recommended protocol.