Find a Product

U-18666A

U 18666A is a small molecule inhibitor of cholesterol transport from endosomes/lysosomes to the endoplasmic reticulum in a variety of cell types, including macrophages and sympathetic neurons. Also weakly inhibits hedgehog signaling. Implicated in multiple diseases including Neimann-Pick disease type C (NPC), alzheimer's, cataracts, and atherosclerosis.

Catalog No. Size Price Quantity
92-1094 5 mg $186.00

For account specific pricing, please contact Customer Service at customerservicedrx@eurofins.com.
Description
U-18666A
Compound Type
Agonist
Storage
≤ -20◦C
Source
Synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control compound, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.