Products / Reagent / 92-1138
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Troglitazone

Troglitazone is a synthetic antidiabetic and anti-inflammatory drug previously prescribed to patients with type 2 diabetes mellitus, but was withdrawn from the market in 2000 due to toxicity issues. Selective agonist of the peroxisome proliferator-activated receptor-γ (PPARγ, EC50=555nM) with no activity for PPARα or PPARδ.

Catalog No. Size Price Quantity
92-1138 5 mg $329.00
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Description
Troglitazone
Compound Type
Agonist
Storage
≤ -20◦C
Source
Synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control compound, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.