TIP-39

Tuberoinfundibular peptide of 39 residues (TIP 39) is a neuropeptide protein related to parathyroid hormone that is a potent and selective agonist of parathyroid hormone 2 receptor (PTH2R), resulting in adenyl cyclase activation and elevation of intracellular calcium levels. Also plays a role in protein kinase C beta activation, beta-arrestin recruitment, PTH2R internalization, cell proliferation inhibition, and possibly spermatogenesis and nociceptive circuit activation. Has little influence on PTH1R.

Catalog No. Size Price Quantity
92-1071 1 mg $797.00

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Description
TIP-39
Compound Type
Agonist
Storage
≤ -20◦C
Source
Synthetic
Cells were plated in a 96-well plate and stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected according to the recommended protocol.