Recombinant Human TNF alpha

Tumor necrosis factor alpha (TNFα) is an endogenous pyrogen cytokine that plays a key part in regulating immune cells, immume response to infection, and systemic inflammation. Also regulates cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Is implicated in multiple autoimmune disorders due to its role in inflammation, including inflammatory bowel disease, rheumatoid arthritis, ankylosing spondylitis, and psoriasis. Agonist of TNF receptor 1 and 2.

Catalog No. Size Price Quantity
92-1097 10 µg $135.00

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Description
Recombinant Human TNF alpha
Compound Type
Agonist
Storage
≤ -20◦C
Source
E. coli
Cells were plated in a 384-well plate and incubated at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control compound, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.