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Recombinant Human IL-6

Interleukin 6 (IL-6) is a pro-inflammatory cytokine protein and intricate member of the immune response. Also acts as an anti-inflammatory myokine. Secreted by T cells, macrophages, osteoblasts, and smooth muscle cells for a variety of functions, including stimulating immune response for bacterial infection, burns, trauma, inducing fever, stimulating osteoclast formation, and inducing inflammation. Also inhibits TNF-alpha and IL-1 and activates IL-1ra and IL-10, leading to anti-inflammatory activity. Agonist of the IL-6 receptor, and implicated in multiple inflammatory diseases, including systemic juvenile rheumatoid arthritis and diabetes mellitus susceptibility.

Catalog No. Size Price Quantity
92-1285 20 µg $383.00

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Description
Recombinant Human IL-6
Compound Type
Agonist
Storage
-20°C
Source
Recombinant
Cells were seeded in a 96-well plate, incubated at 37°C / 5% CO₂ followed by stimulation with a control ligand, as defined in the assay conditions below. After stimulation, assay signal was detected using the PathHunter® detection kit according to the recommended protocol.