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Recombinant Human Angiopoietin-2

Angiopoietin-2 (ANGPT2) is a modulating antagonist of angiopoietin-1 (ANGPT1) and TIE2, binding to TIE2 and competing with ANGPT1. Can induce tyrosine phosphorylation of TIE2, and may facilitate endothelial cell apoptosis and vascular regression through loosening of cell-matrix contacts. May also contribute to angiogenic signaling via stimulation of endothelial cell migration and proliferation.

Catalog No. Size Price Quantity
92-1293 25 µg $538.00

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Recombinant Human Angiopoietin-2
Compound Type
Cells were plated in a 384-well plate and incubated at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.