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L-165,041

L-165,041 is a small molecule agonist of the phenyloxyacetate PPAR-delta receptor (Ki=6nM), >100-fold selective vs other PPAR receptors. Has neuroprotective properties in cerebral infarction and Parkinson's disease. It is less potent and selective than GlaxoSmithKline's other PPARδ inhibitor, GW 501516.

Catalog No. Size Price Quantity
92-1130 10 mg $321.00

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Description
L-165,041
Compound Type
Agonist
Storage
23-25°C
Source
Synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control compound, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.