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GW7647

GW 7647 is a synthetic small molecule agonist of the peroxisome proliferator-activated receptor-alpha (PPARα) transcription factor, which is involved in lipid homeostasis regulation. Binds PPARα, PPARγ, and PPARδ with EC50 of 1-10nM, ~1uM, and 1-10uM respectively. Exhibits anti-inflammatory properties, reduces NO production in macrophages, and has lipid-lowering effects.

Catalog No. Size Price Quantity
92-1134 5 mg $334.00
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Description
GW7647
Compound Type
Agonist
Storage
23-25°C
Source
Synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control compound, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.