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Bromosporine

Bromosporine is a synthetic small molecule pan-bromodomain inhibitor developed by the Structural Genomics Consortium for research. Used in research labs, and is shown to accelerate FRAP recovery of BRD4 and CREBBP in cells at 1uM concentration. Bromodomains are implicated in multiple cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction.

Catalog No. Size Price Quantity
92-1239 10 mg $485.00

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Description
Bromosporine
Compound Type
Antagonist
Storage
2-8°C
Source
Synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control compound, using the assay conditions described below. Following treatment, signal was detected using the InCELL Hunter Detection Kit according to the recommended protocol.