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BAM (8-22)

BAM (8-22) is a opioid peptide fragment of the bovine adrenal medulla (BAM22) neuropeptide that is involved in inflammation, pain, and morphine tolerance. Induces itch and nociceptive sensations. Lacks the met-enkephalin motif of BAM22, hence lacking affinity for opioid receptors. Selective agonist of the sensory neuron specific receptors SNSR3 and SNSR4 (EC50=28 and 14nM, respectively).

Catalog No. Size Price Quantity
92-1215 1 mg $570.00

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Description
BAM (8-22)
Compound Type
Agonist
Storage
-20°C
Source
Synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.