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7α,25-dihydroxycholesterol

7α,25-dihydroxycholesterol (7α,25-DHC) is a potent and selective agonist of the G protein-coupled receptor GPR183 (KD=450pM). Acts as a potent chemokine, directing migration of B,T, and dendritic cells, and plays an important role in adaptive immune response.

Catalog No. Size Price Quantity
92-1186 5 mg $509.00
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Description
7α,25-dihydroxycholesterol
Compound Type
Agonist
Storage
≤ -20◦C
Source
Synthetic
Cells were plated in a 96-well plate and stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected according to the recommended protocol.