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2-Cl-IB-MECA

2-Cl-IB-MECA is a potent and selective agonist of A3 adenosine receptor (ADORA3, Ki=0.33nM). Selective over A1 and A2 receptors by 2500- and 1400-fold, respectively. ADORA3 has been implicated in cardioprotective functions during ischemia, neuroprotection and neurodegeneration, as well as cell proliferation and cell death mediation.

Catalog No. Size Price Quantity
92-1045 10 mg $609.00
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Description
2-Cl-IB-MECA
Compound Type
Agonist
Storage
Desiccate at +4°C
Source
Synthetic
Cells were plated in a 96-well plate and stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected according to the recommended protocol.