IRE2, active

N-terminal 6His-tagged, recombinant, human IRE2, amino acids 505-end. IRE2 enables several functions, including ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. IRE2 is also involved in several processes, including apoptotic chromosome condensation; negative regulation of transcription, DNA-templated; and rRNA catabolic process. Predicted to be located in endoplasmic reticulum membrane and endoplasmic reticulum quality control compartment. Predicted to be integral component of membrane. Predicted to be part of IRE1-TRAF2-ASK1 complex. [provided by Alliance of Genome Resources, Apr 2022]

Catalog No. Size Price Quantity
16-054M 250 µg $2,889.00
16-054 10 µg $359.00

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Target
IRE2
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
56 kDa
Accession Number
NM_033266.2
Species
Human
Tag
6His
Purity
93% by SDS-PAGE and Coomassie blue staining
Purification Method
Immobilized metal affinity chromatography
Content
1.15 mg/ml of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.1% 2-mercapteothanol, 300 mM Imidazole, 20% glycerol. Frozen solution.
Storage
1 year at -70°C
Bulk Sizes
Inquire