Abl (T315I), active

N-terminal 6His-tagged recombinant, human Abl, amino acids 27-end containing the T315I mutation. Contains the gatekeeper mutation T315I in the ATP-binding domain. This mutation decreases the sensitivity to Gleevec® by more than 200-fold as compared to the wild type sequence.

Catalog No. Size Price Quantity
14-522M 250 µg $2499.00
14-522 10 µg $399.00

For account specific pricing, please contact Customer Service at customerservicedrx@eurofins.com.

Related Family Members:

Target
Abl
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
121kDa
Accession Number
NM_005157.3; NM_007313.2
Species
Human
Tag
6His
Purification Method
Ni2+/NTA-agarose
Storage
6 months at -70°C
Bulk Sizes
Inquire