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PathHunter® U2OS VISTA/VISTA Dimerization Cell Line

The PathHunter® Dimerization assay detects ligand induced dimerization of two subunits of a receptor-dimer pair. The cells have been engineered to co-express one receptor subunit fused to Enzyme Donor (ED), and a second dimer partner fused to Enzyme Acceptor (EA). Cytoplasmic tail may have been deleted from one or both receptors. Binding of an agonist to one receptor subunit induces it to interact with its dimer partner, forcing complementation of the two enzyme fragments. This results in the formation of a functional enzyme that hydrolyzes a substrate to generate a chemiluminescent signal.

Catalog No. Size Price Quantity
93-1079C3 Clone $19995.00

Related Family Members:

Receptor Family
T cell receptor (inhibitory)
Coupling
N/A
Accession Number
NM_022153.1
Species
Human
Prolink™ Tag
PK1
Cell Background
U2OS
Agonist/Ligand
Human VISTA Antibody
  • [User Manual] cAMP Hunter™ Exenatide Bioassay Kit

    cAMP Hunter Exenatide Bioassay Kits provide a functional, robust, highly sensitive, and easy-to-use cell-based assay to study Exenatide potency and neutralizing antibodies. The bioassay kits contain all the reagents needed for a complete assay including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The pre-qualifie...

    [User Manual] cAMP Hunter™ Exenatide Bioassay Kit

Please refer to the datasheet above for a complete list of required and recommended products.

Select Required Products

Cat. No. Description Size Price Quantity
93-0247 PathHunter® Flash Detection Kit 125 mL (10 plates), 1,000/4,000 dp (96-well/384-well) $3313.00
92-3103G AssayComplete™ Cell Culture Kit-103 Kit $339.00
93-0563R5A AssayComplete™ Cell Plating 5 Reagent 100 mL $299.00


Select Recommended Products

Cat. No. Description Size Price Quantity
92-1311 Anti-VISTA Antibody [730804] 25 µg $250.00
92-0013 384-well Clear bottom TC Treated, Sterile WCB, FB w/ LID 10 plates/pk $179.00
92-0015 384-well White bottom TC Treated, Sterile w/ LID 10 plates/pk $179.00
92-0009 AssayComplete™ Cell Detachment Reagent 50 mL $89.00
92-0011 Green V-Bottom PP Ligand Dilution Plates 10 plates/pk $69.00