PathHunter® U2OS mFCGR2B Clustering Cell Line

The Path Hunter mFcyRIIb clustering cell line is a stable, engineered cell line designed to increase signal produced from a Checkpoint Cell Line via antibody-mediated crosslinking of the receptors. This product is a companion product used to determine cross-linking based increases in potency of agonist antibodies. The cell line included overexpresses mFcyRIIb Fcg receptor. When co-cultured with a Checkpoint Cell Line in the presence of agonist antibody, the Fcg receptor binds to the antibody, inducing receptor clustering. The induced receptor clustering leads to increased activation and downstream signaling, leading to increased EFC signal production. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein.

Catalog No. Size Price Quantity
93-1139C3 2 Vials $10,125.00

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Related Family Members:

Receptor Family
IgSF (Immunoglobulin Fc receptor)
Accession Number
Receptor Species
Prolink™ Tag
Cell Background