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PathHunter® U2OS CD86 Ligand Cell Line

Checkpoint Ligand Cell Lines are companion products to the Checkpoint Signaling Assays, which have been engineered to exogenously express a cell surface ligand for a specific checkpoint receptor. When co-cultured with its cognate receptor-expressing cells, the ligand expressed on the Ligand Cell Line will engage with the checkpoint receptor on the Checkpoint Signaling Cell Line. This receptor-ligand engagement leads to receptor activation and downstream signaling events, which are detected by the forcing complementation of the two β-galactosidase enzyme fragments: EA-tagged SH2 domain and PK-tagged checkpoint receptor. The resulting functional enzyme hydrolyzes substrate to generate a chemiluminescent signal.

Catalog No. Size Price Quantity
93-1093C3 2 vials $9945.00

For account specific pricing, please contact Customer Service at info@discoverx.com.

Related Family Members:

Receptor Family
T cell receptor ligand (inhibitory)
Coupling
N/A
Accession Number
NM_175862.4
Species
Human
Prolink™ Tag
None
Cell Background
U2OS
Agonist/Ligand
Anti-CTLA4 Antibody [14D3]
Antagonist/Inhibitor
Anti-CTLA4 Antibody

Please refer to the datasheet above for a complete list of required and recommended products.

Select Required Products

Cat. No. Description Size Price Quantity
93-0933 PathHunter® Bioassay Detection Kit 50 mL (1,000 dp, 96-well) $4497.00
92-3103G AssayComplete™ Cell Culture Kit-103 Kit $329.00
92-5103FR AssayComplete™ Freezing Reagent F3 2 x 50 mL $279.00
93-0563R0A AssayComplete™ Cell Plating 0 Reagent 100 mL $279.00
92-4103TR AssayComplete™ Thawing Reagent T3 100 mL $229.00
92-0009 AssayComplete™ Cell Detachment Reagent 50 mL $89.00
92-0028 AssayComplete™ Puromycin 1 mL $69.00