PrecisION® hnAChR α4/α6/β2 Recombinant Stable Cell Line

This product has been discontinued. Please contact Technical Support for more information regarding custom development or alternate products.

The α6 subtype of nicotinic receptors has been less studied due in part to the inability to express alpha 6 as the sole alpha subunit. In addition, the α6 subunit may be co-expressed with other alpha subunits, such as the hnAChR α4 subunit. The α4α6β2 nicotinic acetylcholine receptors are highly expressed in mesostriatal and nigrostriatal dopaminergic systems. These receptors could be potential targets for treatment of Parkinson’s disease and addictive behaviors.

Catalog No. Size Price Quantity
CYL3107 2 Vials Inquire

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Application
Electrophysiology assay (Conventional and automated patch clamp platforms)
Family
Ligand-Gated
Target
nAChR α4/α6/β2
Accession Number
NM_000744.6; NM_000748.2; NM_004198.3
Species
Human
Host Cell Type
HEK 293
Content
2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO
Storage
Vials are to be stored in vapor phase of liquid N2