PrecisION® hERG Recombinant Stable Cell Line

The FDA, ICH S7B guidelines set out a non-clinical testing strategy to assess the effects of pharmaceuticals on ventricular repolarisation and proarrhythmic risk. The most common mechanism for this is inhibition of the delayed rectified potassium current IKr. The human ether-à-go-go-related gene (hERG) encodes the potassium ion channel responsible for IKr.

Catalog No. Size Price Quantity
CYL3038 2 Vials Inquire

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Application
Electrophysiology assay (Conventional and automated patch clamp platforms)
Family
Potassium, Voltage-Gated
Target
hERG
Accession Number
U04270
Species
Human
Host Cell Type
CHO-K1
Content
2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO
Storage
Vials are to be stored in vapor phase of liquid N2