PathHunter® HepG2 IL11R STAT3 Signaling Pathway Reporter Cell Line

The PathHunter Signaling Pathway Reporter Assays are stable clonal cell lines that monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC) technology. Each stable cell line is engineered to express a synthetic DNA reporter construct, comprising a pathway-specific transcription factor response element that drives expression of ePL-tagged reporter protein. The activated signaling pathway induces expression of the ePL-tagged reporter protein, which is measured by addition of the detection reagent containing EA, resulting in complementation of the two enzyme fragments, and production of an active enzyme that hydrolyzes the substrate to generate a chemiluminescent signal.

Catalog No. Size Price Quantity
93-1168C044 2 vials $16,479.00

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Receptor Family
Interleukin Receptor
Coupling
N/A
Accession Number
NM_001142784.2
Receptor Species
Human
Cell Background
HepG2
Agonist/Ligand
IL-11
  • [User Manual] PathHunter® Signaling Pathway Reporter Assay

    The PathHunter Signaling Pathway Reporter Assays are stable clonal cell lines used for monitoring the activation of various signaling pathways. Ligands (for example, CD40, IL-6 etc.) bind to distinct receptors and trigger specific signaling pathways. Transcription factors are then activated, followed by their nuclear translocation. Binding of these activated transcription factors to s...

    [User Manual] PathHunter® Signaling Pathway Reporter Assay

Please refer to the datasheet above for a complete list of required and recommended products.

Select Required Products

Cat. No. Description Size Price Quantity
93-0001 PathHunter® Detection Kit 75 mL (10 plates), 1,000/4,000 dp (96-well/384-well) $2,857.00
92-3103G AssayComplete™ Cell Culture Kit-103 Kit $379.00
92-5103FR AssayComplete™ Freezing Reagent F3 2 x 50 mL $329.00
93-0563R5A AssayComplete™ Cell Plating 5 Reagent 100 mL $329.00
92-4103TR AssayComplete™ Thawing Reagent T3 100 mL $249.00
92-0029 AssayComplete™ Hygromycin B 20 mL $227.00
92-0030 AssayComplete™ G418 20 mL $227.00
92-0009 AssayComplete™ Cell Detachment Reagent 50 mL $109.00