PathHunter® HEK 293 CD27 NF-kB Signaling Pathway Reporter Cell Line

The PathHunter Signaling Pathway Reporter Assays are stable clonal cell lines that monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC) technology. Each stable cell line is engineered to express a synthetic DNA reporter construct, comprising a pathway-specific transcription factor response element that drives expression of ePL-tagged reporter protein. The activated signaling pathway induces expression of the ePL-tagged reporter protein, which is measured by addition of the detection reagent containing EA, resulting in complementation of the two enzyme fragments, and production of an active enzyme that hydrolyzes the substrate to generate a chemiluminescent signal.

Catalog No. Size Price Quantity
93-1166C1 2 vials $15,999.00

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Receptor Family
Tumor Necrosis Factor Receptor Superfamily Receptor
Coupling
N/A
Accession Number
NM_001242.5
Receptor Species
Human
Cell Background
HEK 293
Agonist/Ligand
CD27L