PathHunter® U2OS VISTA/VISTA Dimerization Cell Line

The PathHunter VISTA/VISTA Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand induced dimerization of VISTA/VISTA receptors. This product uses EFC technology. The cell line included overexpresses VISTA target protein fused to PK alongside VISTA target protein fused to EA. Upon ligand-induced dimerization of VISTA/VISTA , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.

Catalog No. Size Price Quantity
93-1079C3 2 vials $20,799.00

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Related Family Members:

Receptor Family
T cell receptor (inhibitory)
Accession Number
Cell Background
  • [User Manual] PathHunter® Dimerization Assay

    PathHunter® Dimerization Assays provide a robust, highly sensitive and easy-to-use cell-based functional assay to study various protein activities in a cell. The assays allow for the monitoring of receptor-receptor interactions at the&...

    [User Manual] PathHunter® Dimerization Assay