PathHunter® U2OS TrkB-P75 Bioassay Kit

PathHunter® Bioassay kits provide a robust, highly reproducible and easy-to-use, cell-based functional assay to study receptor activity through a chemiluminescent output. The bioassay kits contain the reagents needed for a functional assay including ready-to-assay cells, plating, dilution & detection reagents, positive control agonist and assay plates. The ready-to-assay kits are designed to accelerate and simplify development of a QC potency assay or a NAb assay for biologic drugs.

Catalog No. Size Price Quantity
93-0530Y3-00076 1000 dp (10 x 96-well) $7,729.00
93-0530Y3-00075 200 dp (2 x 96-well) $2,249.00

For account specific pricing, please contact Customer Service at

Related Family Members:

Neurotrophic tyrosine kinase receptor type 2
Receptor Tyrosine Kinase
SH2 Domain
Cell Background
Accession Number
Recombinant Human BDNF
Assay Measures
SH2 Recruitment
Bioassay Target Name
Assay Qualified With
Cells expressing human ErbB1 receptor were seeded in Cell Plating 17 Reagent and incubated with increasing concentrations of an anti-ErbB1 MAb, keeping agonist, human EGF, constant at the EC80 according to the protocol. ErbB1 Bioassay Kit is able to detect a dose dependent neutralization of receptor signaling as increasing concentrations of anti-ErbB1 mAb bind directly to the receptor and block EGF ligand signaling.
See User Manual for Product Configuration Details
Short term (<24 h): Store at -80°C; Long term (>24 h): Store in vapor phase of liquid nitrogen.
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