PathHunter® Panitumumab Bioassay Kit

The PathHunter® Dimerization Bioassay detects ligand induced dimerization of two subunits of a receptor-dimer pair. The cells have been engineered to co-express one receptor subunit fused to Enzyme Donor (ED), and a second dimer partner fused to Enzyme Acceptor (EA). Cytoplasmic tail may have been deleted from one or both receptors. Binding of an agonist to one receptor subunit induces it to interact with its dimer partner, forcing complementation of the two enzyme fragments. This results in the formation of a functional enzyme that hydrolyzes a substrate to generate a chemiluminescent signal.

Catalog No. Size Price Quantity
93-1051Y3-00094 1000 dp (10 x 96-well) $8,259.00
93-1051Y3-00093 200 dp (2 x 96-well) $2,399.00

For account specific pricing, please contact Customer Service at

Related Family Members:

Epidermal growth factor receptor
Receptor Tyrosine Kinase
Cell Background
Accession Number
Recombinant Human EGF
Vectibix (Panitumumab)
Assay Measures
EGFR/ErbB2 Dimerization
Bioassay Target Name
Assay Qualified With
Drug Trademark Owner
‎Vectibix® is a registered trademark of Amgen Inc.
The above graph is an example of a typical dose-response curve for the Panitumumab Bioassay, generated using the protocol outlined in the user manual. Data was acquired using the EnVision Microplate Reader (PerkinElmer).
See User Manual for Product Configuration Details
Short term (<24 h): Store at -80°C; Long term (>24 h): Store in vapor phase of liquid nitrogen.
  • [User Manual] PathHunter® Panitumumab Bioassay Kit

    PathHunter Panitumumab Bioassay kits provide a functional, robust, highly sensitive, and easy-to-use cell-based assay to study panitumumab potency and neutralizing antibodies. The bioassay kits contain all the reagents needed for a complete assay including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The pre-valid...

    [User Manual] PathHunter® Panitumumab Bioassay Kit