PathHunter® CHO-K1 MRGPRX2 Bioassay Kit

The PathHunter MRGPRX2 Bioassay kit provides a robust, highly sensitive, and easy-to-use functional cell based assay to determine drug potency and detect neutralizing antibodies. The bioassay kit contains all the materials needed for a complete assay, including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility, and faster implementation from characterization to lot release.

Catalog No. Size Price Quantity
93-0309Y2-00144 1000 dp (10 x 96-well) $7,729.00
93-0309Y2-00143 200 dp (2 x 96-well) $2,249.00

For account specific pricing, please contact Customer Service at customerservicedrx@eurofins.com.

Related Family Members:

Target/Description
MAS-related GPR, member X2
Group
Class A Orphan
Cell Background
CHO-K1
Species
Human
Accession Number
NM_054030.2
Agonist/Ligand
Cortistatin 14
Assay Measures
β-Arrestin
Bioassay Target Name
MRGPRX2
Assay Qualified With
Cortistatin 14
The following graph is an example of a typical dose response curve for the MRGPRX2 Bioassay generated using the protocol outlined in this manual. The data shows potent, dose-dependent recruitment of β-arrestin, when treated with Cortistatin-14.
Format
See User Manual for Product Configuration Details
Storage
Short term (<24 h): Store at -80°C; Long term (>24 h): Store in vapor phase of liquid nitrogen.
β-Arrestin Isoform
β-Arrestin-2
Coupling
Gq