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PathHunter® Bevacizumab Bioassay Kit

The PathHunter® Dimerization Bioassay detects ligand induced dimerization of two subunits of a receptor-dimer pair. The cells have been engineered to co-express one receptor subunit fused to Enzyme Donor (ED), and a second dimer partner fused to Enzyme Acceptor (EA). Cytoplasmic tail may have been deleted from one or both receptors. Binding of an agonist to one receptor subunit induces it to interact with its dimer partner, forcing complementation of the two enzyme fragments. This results in the formation of a functional enzyme that hydrolyzes a substrate to generate a chemiluminescent signal.

Catalog No. Size Price Quantity
93-0996Y1-00002 1000 dp (10 x 96-well) $8251.00
93-0996Y1-00001 200 dp (2 x 96-well) $2352.00

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Related Family Members:

Kinase Insert Domain Receptor
Receptor Tyrosine Kinase
Cell Background
HEK 293
Accession Number
Assay Measures
Bioassay Target Name
Assay Qualified With
Drug Trademark Owner
Avastin® is a registered trademark of Genentech, Inc.
See User Manual for Product Configuration Details
Short term (<24 h): Store at -80°C; Long term (>24 h): Store in vapor phase of liquid nitrogen.
  • [User Manual] PathHunter® Bevacizumab Bioassay Kit

    PathHunter® Bevacizumab Bioassay kits provide a robust, highly sensitive and easy-to-use, cell-based functional assay to study bevacizumab potency and neutralizing antibodies. The bioassay kits contain all the reagents needed for a complete assay including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates...

    [User Manual] PathHunter® Bevacizumab Bioassay Kit