InCELL Hunter™ HEK 293 BAZ2A Bromodomain Cell Line

Background Information:

The InCELL Hunter™ HEK 293 BAZ2A Bromodomain Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with regulators of epigenetics pathways. This cell line enables assessment of compound-engagement-based stabilization of BAZ2A via detection of BAZ2A levels. This product uses EFC technology. The cell line included overexpresses BAZ2A target protein fused to PL. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal.
This stable engineered cell line is provided as two vials of cryopreserved cells.

Target Class:

Epigenetic

Family:

Bromodomain-Containing

Sub Family:

Reader

Protein Name:

BAZ2A

Protein Aliases:

TTF-I interacting peptide 5

Accession Number:

NM_013449.3

UniProt Number:

Q9UIF9

Gene Name:

BAZ2A

Gene ID:

11176

Gene Aliases:

KIAA0314|TIP5|WALp3

Target Species:

Human

Cell Background:

HEK293