KINOMEscan® KIT(V559D,T670I)

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Panel:

Target/Description
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Group
TK
Kinase Construct
Partial Length
Accession Number
NP_000213.1
Species
Human
Kinase Form
Mutation (V559D,T670I)
Expression System
Bacterial
Amino Acid Start/Stop
Y545/D952

Assay Information

Average Z' Panel
0.76

Reference Inhibitor Information (all values in nM)

Compound
KD
Sunitinib
0.28
AMG-706
13
AST-487
18
PKC-412
150
MLN-518
1100
Imatinib
2900