KINOMEscan® FLT3(K663Q)

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Panel:

Target/Description
fms-related tyrosine kinase 3
Group
TK
Kinase Construct
Partial Length
Accession Number
NP_004110.2
Species
Human
Kinase Form
Mutation (K663Q)
Expression System
Bacterial
Amino Acid Start/Stop
V592/Y969

Assay Information

Average Z' Panel
0.72

Reference Inhibitor Information (all values in nM)

Compound
KD
Sunitinib
0.22
MLN-518
1.5
PKC-412
2
Sorafenib
4.5
CGP-52421
19
CEP-701
5.4