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KINOMEscan® FLT3(ITD)

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Panel:

Target/Description
fms-related tyrosine kinase 3
Group
TK
Kinase Construct
Partial Length
Accession Number
NP_004110.2
Species
Human
Kinase Form
Mutation (ITD)
Expression System
Bacterial
Amino Acid Start/Stop
Null

Assay Information

Average Z' Panel
0.76

Reference Inhibitor Information (all values in nM)

Compound
KD
Sunitinib
0.99
CHIR-258/TKI-258
3.6
ABT-869
8.8
MLN-518
9.1
PKC-412
11
CEP-701
1.5