KINOMEscan® FLT3(D835H)

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Panel:

Target/Description
fms-related tyrosine kinase 3
Group
TK
Kinase Construct
Partial Length
Accession Number
NP_004110.2
Species
Human
Kinase Form
Mutation (D835H)
Expression System
Bacterial
Amino Acid Start/Stop
V592/Y969

Assay Information

Average Z' Panel
0.75

Reference Inhibitor Information (all values in nM)

Compound
KD
ABT-869
2.7
Sunitinib
4.3
CHIR-258/TKI-258
6.1
PKC-412
6.8
MLN-518
310
CEP-701
0.66