Biological Information
Background Information:
Rsk1/MAPKAP Kinase 1a is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) Signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. GenBank NM_002953
Target Class:
Kinase
Family:
AGC
Sub Family:
Protein Ser/Thr
Protein Name:
RSK1
Protein Aliases:
90 kDa ribosomal protein S6 kinase 1|p90-RSK 1|p90RSK1|p90S6K|MAP kinase-activated protein kinase 1a|MAPK-activated protein kinase 1a|MAPKAP kinase 1a|MAPKAPK-1a|Ribosomal S6 kinase 1|RSK-1
Accession Number:
NM_001006665.1; NM_002953.3
UniProt Number:
Q15418
Gene Name:
RPS6KA1
Gene ID:
6195
Gene Aliases:
RSK|RSK1|HU-1|p90Rsk
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology