Rsk1/MAPKAP Kinase 1a, active

Background Information:

Rsk1/MAPKAP Kinase 1a is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) Signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. GenBank NM_002953

Target Class:

Kinase

Family:

AGC

Sub Family:

Protein Ser/Thr

Protein Name:

RSK1

Protein Aliases:

90 kDa ribosomal protein S6 kinase 1|p90-RSK 1|p90RSK1|p90S6K|MAP kinase-activated protein kinase 1a|MAPK-activated protein kinase 1a|MAPKAP kinase 1a|MAPKAPK-1a|Ribosomal S6 kinase 1|RSK-1

Accession Number:

NM_001006665.1; NM_002953.3

UniProt Number:

Q15418

Gene Name:

RPS6KA1

Gene ID:

6195

Gene Aliases:

RSK|RSK1|HU-1|p90Rsk

Target Species:

Human