WNK3, active

Background Information:

Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]). GenBank NM_020922

Target Class:

Kinase

Family:

Other Protein Kinase

Sub Family:

Protein Ser/Thr

Protein Name:

WNK3

Protein Aliases:

Protein kinase lysine-deficient 3|Protein kinase with no lysine 3

Accession Number:

NM_001002838.1; NM_020922.2

UniProt Number:

Q9BYP7

Gene Name:

WNK3

Gene ID:

65267

Target Species:

Human