SAPK4, unactive

Background Information:

SAPK4 is a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. SAPK4 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2.

Target Class:

Kinase

Family:

CMGC

Sub Family:

Protein Ser/Thr

Protein Name:

p38delta (SAPK4)

Protein Aliases:

MAPK 13|Mitogen-activated protein kinase p38 delta|MAP kinase p38 delta|Stress-activated protein kinase 4

Accession Number:

Y10488

UniProt Number:

O15264

Gene Name:

MAPK13

Gene ID:

5603

Gene Aliases:

SAPK4|p38delta|PRKM13|SAPK4

Target Species:

Human